Roche and its subsidiary TIB Molbiol have developed a series of tests for the detection of the monkeypox virus, the Switzerland-based pharmaceutical company announced.
The monkeypox virus is a close relative of the smallpox virus, belonging to orthpoxviridae in the poxviridae family.
The modular virus detection tool, called LightMix, includes three orthpoxvirus detection kits with different functions, Roche said in a statement. The first kit detects orthpoxvirus; The second kit tests only for monkeypox virus (west and Central African branches); The third kit contains the main functions of the first two kits, showing specific information on the presence of the monkeypox virus (west and Central African branches) as well as the detection of orpoxvirus.
Thomas Schinek, a Roche executive, said the new test could detect monkeypox and help track its spread. Such diagnostic tools are critical for addressing and ultimately managing emerging public health challenges, as they advance responses such as tracking efforts and treatment strategies.
The monkeypox virus was first identified in 1958 in a group of monkeys used for research when the animals developed a "pox-like" infection, hence the name. Since May, several non-endemic countries have reported human cases of the monkeypox virus, including the United Kingdom, the United States, Portugal, Spain, and Italy.
Affected by the ever-changing international situation, the supply and prices of international bulk fumed silica are still very uncertain.
Fumed silica is a kind of inorganic nanomaterial with a small particle size, large specific surface area, and high surface activity.
It is mainly used as a rheological auxiliary agent in paint and coating, which can effectively prevent flow hanging and thick edges in the construction process and improve construction efficiency.
In addition, silica in the coating is also used as an anti-sedimentation and dispersant aid, can effectively prevent the sedimentation of the pigment delamination, improve the coating weather resistance, scratch resistance, and the bonding strength between the coating and the substrate.
Fumed silica is an ideal anti-sedimentation agent, its hydrogen bond structure is very stable and uniform, and it is a three-dimensional network structure, which is very effective to prevent the precipitation of pigment in the coating system. Especially for the color paste system, the appropriate amount will greatly improve the stability of color paste, and can reduce the amount of wetting dispersant, to improve the applicability of color paste and reduce the influence of color paste on the coating system. At the same time, the anti-sedimentation effect of fumed silica is very beneficial to the storage of coatings, especially some pigments such as metal powder and thin sections, which are easy to precipitate and cannot be completely suspended, the use of fumed silica can ensure that its dispersion does not precipitate.
The precipitation of fumed silica is very beneficial for coating storage and transportation. For some pigments, such as metal powder and thin film, it is easy to precipitate and cannot be effectively suspended. The use of fumed silica can ensure that the mixture is uniform and does not cause sedimentation. In absolute non-polar liquid phase, such as hydrocarbons (hydrocarbons) without hydrogen bond (chemical structure such as R-H) bonding ability, halogenated hydrocarbon (halogen and hydrocarbon electrophilic addition or substitution reaction) solvent, the viscosity recovery time is only a fraction of a second; Thixotropic recovery in polar liquids, such as hydrogen-bonded amines (R-NH3), alcohols (R-OH), carboxylic acids (R-COOH), aldehydes (R-CHO), and dialcohols (such as Ho-Rh2-OH, where R- is a saturated alkyl group), can take up to several months, depending on the amount of fumed silica added and the uniformity of mixing. The fumed silica is pre-dispersed and added to the finished paint. Usually, a high-speed dispersing machine or three-roller machine is used to improve the dispersion effect. If the dispersion is not good, the paint film will have particles, affecting gloss and aesthetics.
In addition, as an anti-sedimentation agent, fumed silica is added to coppery acrylic resin conductive coating. The test proves that it can make the thermoplastic acrylic resin thixotropic and prevent the deposition of filler particles, but if the addition amount is too much, the coating becomes a gel state, the conductivity of the coating would be reduced.
In the powder system, because of the small particle size and high surface energy, silica can be adsorbed on the surface of the coating powder, and form a surface layer on the surface of the powder to improve the dispersion of the powder. In the same coating system, the addition of fumed silica can obviously shorten the dispersion time and improve the production efficiency.
The addition of fumed silica in wall coating can effectively prevent coating from hanging, improve the flatness of the construction surface, and also greatly improve the washing resistance and aging time of exterior wall coating. The bonding strength of coating film and the wall is also greatly improved, the hardness of coating film is significantly increased, and the surface self-cleaning ability is also improved.
The adsorption of fumed silica on the surface of powder coating can form a movable layer and produce a "ball bearing" effect, which can prevent the powder coating from absorbing moisture and agglomerating and improve the fluidity of powder coating.
The main function of floor paint is the rheological control, improving the weatherability and scratch-resistance of floor paint, and improving the leveling performance of the coating.
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For Germany, the largest economy in Europe, the impact of the Russian-Ukrainian conflict on the natural gas market is the most obvious. This also exposed the serious dependence of some German industrial enterprises on Russian natural gas. Some analysts pointed out that the instability of natural gas supply has had a big impact on the German economy and threatened its market competitiveness because alternative energy supplies will not be cheap and difficult to come quickly. Increased uncertainty over natural gas supplies is putting enormous pressure on German manufacturers in sectors ranging from steelmaking to chemical fumed silica for the time being, but the market demand for fumed silica in the future will also change with the influence of various external factors. If you need fumed silica, please feel free to contact us.
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